The physiological role of liver alcohol dehydrogenase
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The physiological role of liver alcohol dehydrogenase.
1. Yeast alcohol dehydrogenase was used to determine ethanol in the portal and hepatic veins and in the contents of the alimentary canal of rats given a diet free from ethanol. Measurable amounts of a substance behaving like ethanol were found. Its rate of interaction with yeast alcohol dehydrogenase and its volatility indicate that the substance measured was in fact ethanol. 2. The mean alcoho...
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To elucidate the role of zinc-bound water in liver alcohol dehydrogenase catalysis, chelation by 1,lO-phenanthroline and 2.2-bipyridine was studied. The rate constants for association of both chelating agents to the active center zinc were pH-dependent with a pK, of 9.2 and preferential binding to a protonated form. The binary complex dissociation rate constants were pHindependent for both chel...
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از محوری ترین اثراتی که یک فیلم سینمایی ایجاد می کند دیالوگ هایی است که هنرپیش گان فیلم میگویند. به زعم یک فیلم ساز, یک شیوه متأثر نمودن مخاطب از اثر منظوره نیروی گفتارهای گوینده, مثل نیروی عاطفی, ترس آور, غم انگیز, هیجان انگیز و غیره, است. این مطالعه به بررسی این مسأله مبادرت کرده است که آیا نیروی فراگفتاری هنرپیش گان به مثابه ی اعمال گفتاری در پنج فیلم هالیوودی در نسخه های دوبله شده باز تولید...
15 صفحه اولKinetic studies of liver alcohol dehydrogenase.
1. NADH2 prepared by enzymic reduction of pure NAD by the method of Rafter & Colowick (1957), and isolated as the sodium salt, gives higher maxrimum rates of reduction of acetaldehyde with liver alcohol dehydrogenase at pH 6 than a number of commercial preparations of high purity. Maximum values of 2-4 for the extinction ratio E260/E340 and 2% for the proportion of inactive material absorbing a...
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The primary enzymes involved in alcohol metabolism are alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Both enzymes occur in several forms that are encoded by different genes; moreover, there are variants (i.e., alleles) of some of these genes that encode enzymes with different characteristics and which have different ethnic distributions. Which ADH or ALDH alleles a person carri...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1970
ISSN: 0306-3283
DOI: 10.1042/bj1180635